Denise Yates

Company: Novartis Institutes of Biomedical Research

Job title: Executive Director, Biomarker Development Cardiovascular & Metabolism Therapeutic Area Head

Seminars:

Reimagining Biomarkers to Illuminate the Right Patient Population & Advance Precision Medicine Impact 4:00 pm

Navigating biomarkers in cardiovascular drug development that span all modalities – genetics, peripheral proteins, lipids, inflammatory markers as well as imaging and device-derived markers De-risking cardiovascular outcome trials with early proof of concept biomarkers remains a major challenge Exploratory omic analyses in cardiovascular outcomes offer hypothesis generation for precision medicineRead more

day: Conference Day 2

Reimagining Biomarkers to Illuminate the Right Patient Population & Advance Precision Medicine Impact 9:00 am

Despite the ignited excitement for a next generation therapeutic with potential to reduce mortality, progress in clinical studies has been hindered by challenges in identifying suitable biomarkers.   Join this interactive deep dive to harness biomarkers to better stratify patient populations and understand how best to target them to unlock the therapeutic potential of cardiovascular…Read more

day: Pre-Conference Workshop Day

Challenges & Opportunities for Imaging & Biomarker Endpoints that Reveal Cardiac & Vascular Remodeling 3:30 pm

Adapting cardiovascular imaging from their diagnostic application into drug development tools can serve multiple biomarker roles (efficacy, selection, safety) Myocardial structure and function endpoints can elucidate therapeutic response if appropriately selected Innovation with these techniques and in combination with peripheral biomarkers will have a role in cardiovascular precision medicineRead more

day: Conference Day 2